Associate Professor Shaun Sandow | UniSC | University of the Sunshine Coast, Queensland, Australia

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Associate Professor Shaun Sandow

PhD ANU

  • Associate Professor, Cardiovascular Physiology
  • School of Health
Email
Telephone
+61 7 5456 5737 / 0411 248 743
Office location
SD-T-3-3.12
Campus
Sunshine Coast
Shaun Sandow

Working with colleagues in Australia, Canada, Britain and Denmark, our studies aim to determine some of the ways that cells in arteries communicate with one another and specifically, at how cells control the balance between the way that arteries narrow (constrict) and enlarge (dilate). This balance is referred to as vascular tone and is the main determinant of blood pressure and thus cardiovascular disease. Coordination of vascular tone is dependent on signals passing through junctions within and between the cellular layers in arteries. Our studies correlate anatomy, function, molecular and biochemical data, to identify the fundamental pathways that underlie blood vessel function and thereby determine targets for the correction of vascular disease.

Professional Memberships 

  • Australian and New Zealand Microcirculation Society (2001-present)
  • Australian Physiological Society (1995-present)
  • Australian Vascular Biology Society (2012-present)
  • Perinatal Society of Australia and New Zealand (2019-present)
  • The Brain Foundation (Australia; 2015-)

Research Grants

Project name Investigator(s) Funding body Year(s) >Funding amount
Identifying treatment targets to improve cerebral blood flow after stroke and hypoxia Dr Shaun Sandow; Dr Tim Murphy; Dr Nicole Jones; Dr Fraser Russell; Dr Rohan Grimley; Dr Andrew Dettrick; Brain Foundation 2016 $34,000
Diabetes Australia Research Trust Millennium Grant Dr Tim Murphy; Dr Shaun Sandow Diabetes Australia 2016-2017 $49,950
GNT1048885 ATP
release from gastrointestinal epithelium: A potential target for the treatment
of slow transient constipation 
Dr Lu Liu; Associate Professor Paul Bertrand; Dr Shaun Sandow National Health and Medical Research Council 2013-2015 $306,806.18
GNT546087 Local mechanisms that determine regional differences in ability of small arteries to deliver blood to organs in diabetes

Associate Professor Helena C Parkington; Dr Shaun L Sandow; Prof Michael Permezel

National Health and Medical Research Council 2009-2012 $735,200
Identifying priority targets for effective blood volume management in preterm infants

CIC with CIA Prof Paul Colditz; CIB Yvone Eiby; CID DR Lingwood (RBWH appointment) and AI Prof Ian Wright

Royal Brisbane Women’s Hospital Foundation Grant 2021 $49,000

Potential Research Projects for HDR & Honours Students

  • Role of endothelial large conductance calcium activated potassium channels in cerebrovascular health and disease (with Tim Murphy and Nicole Jones, University of New South Wales)
  • Identifying targets to correct abnormal blood flow in pregnancy (with Tim Murphy, University of New South Wales; and Leo Leader, Royal Hospital for Women, Sydney)
  • Omega-3 fatty acid supplementation for treatment of abdominal aortic aneurysm — login required (with Fraser Russell, UniSC) 
  • Cardiovascular mechanisms that underlie the pain and aura phases of migraine (with Vladimir Matchkov, Denmark)

Research areas

  • cardiovascular
  • control of vascular tone
  • endothelial and smooth muscle cell biology
  • cell coupling, gap junctions and connexins
  • remodelling in development (pregnancy and growth) and disease, including obesity, diabetes, stroke
  • microdomain signaling

Teaching areas

  • Cardiovascular Physiology

Associate Professor Shaun Sandow's specialist areas of knowledge include cardiovascular, control of vascular tone, cell biology and anatomy.

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