Trial begins to find treatment for knee pain due to osteoarthritis | UniSC | University of the Sunshine Coast, Queensland, Australia

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Trial begins to find treatment for knee pain due to osteoarthritis

Researchers at the University of the Sunshine Coast are trialling a new investigational treatment for knee pain in one knee due to osteoarthritis. Osteoarthritis is the most common form of chronic joint disease, affecting more than one in five Australians over the age of 45.

The causes are complex and still not fully understood, but evidence suggests that it follows changes in chondrocytes (cartilage-forming cells), leading to increased production of degrading enzymes in the affected joint.

UniSC Clinical Trials Principal Investigator Dr Peter De Wet said there were currently no treatments that prevent or significantly slow the progression of osteoarthritis.

"Currently available therapies target the symptoms of osteoarthritis, such as pain and inflammation of the afflicted joint, but fail to address the underlying causes," Dr De Wet said.
Senior man suffering from knee pain walking upstairs

Trial participants would be asked to attend eight visits at the UniSC clinical trials Birtinya clinic on the Sunshine Coast, over a seven-month period.

Clinical trial coordinator Lindley Mattiazzi said the trial sought to assess the safety of an investigational treatment for knee pain due to osteoarthritis.

“We’re looking for people aged 18 years or above, who continue to experience knee pain due to osteoarthritis despite standard of care therapies including regular doses of anti-inflammatories or other pain medication, to participate in the trial,” Ms Mattiazzi said.

Eligible participants must have symptomatic osteoarthritis of the knee.

Learn more about participating in a trial at UniSC Clinical Trials.

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